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My question will not be related to IVF or fertility but to ask your expert opinion on stem cell therapy and autism. As a mother of an profoundly autistic son I’m frustrated about the lack of support and treatment of this situation. I might like your professional opinion on this concern and obtainable options for the treatment. I had a traumatic pregnancy and labour, baby was small is there a corelation? H

Dear H,

As I do know you appreciate, this web site is probably not designed to reply queries not concerned with infertility, so I am not in a position to offer you definitive recommendation about autism or its remedy. However, I actually sympathise with what you face. Stem cell research is indeed a key space of research which the Genesis Research Trust undertakes. Also, as autism is likely to be a problem associated in some solution to early human growth, and it's the intention of the trust to arrange an essential new professorial chair with a research base at Imperial College taking a look at issues related to this, let me give a quick reply.

The analysis of autism includes a wide range of attainable disorders. One downside in making any analysis is establishing a transparent understanding of what the options of this situation are, and the way they differ from particular person to particular person. And sadly, when there may be such a wide range of ill-defined features of any medical situation, no one medical therapy is prone to be really helpful. Because we're such a long way from defining what we imply by ‘autism’ we're nonetheless a great distance from effective therapies in many circumstances. There's a UK charity (www.researchautism.net) which can give you further data and likewise the Autism Society (www.autism.org.uk) which may be able to give you extra assist, significantly about your son’s situation.

You ask whether or not there was any trigger associated with your pregnancy, start or supply of your son. This is highly relevant to our analysis and to this vital new professorial staff we are establishing. Whilst there aren't any real clues in what you say about your own particular case, they are robust pointers which counsel some environmental affect earlier than or throughout pregnancy might enhance the chance of circumstances like autism and we consider that this is such an important space for the long run that we goal to boost £2 - three million pounds to help this type of research via this distinctive professorship.

With regard to stem cell remedy, in the mean time it seems moderately unlikely there it's going to be great breakthrough with stem cells in autistic youngsters in the foreseeable future. Two broad strategies have been tried - one is to inject bone marrow stem cells (or related cells) into individuals with autism into the blood stream - within the hope they will have an effect on brain function ultimately. There are experiences that autistic signs have been improved, https://autismtreatmentcare.com/ however these trials have not been correctly managed and lengthy-term outcomes are not reported. Frankly I'm very sceptical that the evidence is sweet that these cells led to any form of ‘repair’ of mind tissue in such instances. Also the therapy will not be with out appreciable danger and i actually would not encourage one among my family to do this extremely experimental remedy. The other technique which appear much more risky is the injection of cells immediately into the fluid across the spinal cord in the hope they are going to migrate to the brain. So far as I'm aware, this has been tried in a single or two individuals only and it is unclear whether or not there was really any benefit.

I'm sorry to not provide you with more constructive info but it can be crucial that charities like our are supported. Better diagnosis and remedy of these demanding conditions which have an effect on so many many children is urgently needed.